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Measuring 4D flow MRI during exercise offers benefits over stress echo - Health Imaging

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Cardiovascular four-dimensional MRI can measure blood flow during exercise and provides insights into right-sided heart dysfunction that is not well understood via traditional stress echocardiography.

That’s according to a team of University of Wisconsin researchers who performed 4D flow MRI in nine healthy adults during intense cardio and while at rest, sharing their findings June 18 in Radiology: Cardiothoracic Imaging. The approach accurately quantified flow in the ascending aorta (AAo) and main pulmonary artery (MPA) and was “highly” repeatable.

It did take about nine minutes to complete the scan, which would limit the approach to patients who are able to maintain stable exercise during that time period, but it’s an “important first step” to bringing the modality into real-world use, Michael Markl, PhD, and Jeesoo Lee, PhD, of Northwestern University, said in a related editorial.

For their pilot study, Jacob Macdonald, PhD, and colleagues at the Madison, Wisconsin-based institution prospectively performed 4D flow MRI in 11 healthy patients (average age 26 years), nine of whom completed both imaging at rest and while on an MRI-compatible exercise stepper between March 2016 and July 2017.

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Measuring 4D flow MRI during exercise offers benefits over stress echo - Health Imaging
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